null
SMILES Cc1c(CC(O)=O)c2cccnc2n1S(=O)(=O)c1ccc(F)c(F)c1
InChI Key InChIKey=HLSYGDSWXJGENX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 50296848
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]PGD2 from mouse CRTh2 receptor expressed in K562 cellsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]-prostaglandin D2 from human CRTh2 receptor expressed in CHO cells after 2 hrsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against prostaglandin E2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human prostaglandin D2 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against prostaglandin E3 receptorMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against prostaglandin E4 receptorMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against prostaglandin F receptorMore data for this Ligand-Target Pair
TargetThromboxane A2 receptor(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human thromboxane A2 receptorMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of CCKalpha receptorMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 167nMAssay Description:Antagonist activity against mouse CRTh2 receptor expressed in K562 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Antagonist activity at CRTh2 receptor in human isolated eosinophil assessed as inhibition of DK-PGD2-induced shape change after 5 mins by flow cytome...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Novartis Institutes of Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in CHO cells assessed as inhibition of prostaglandin D2 and forskolin-induced cAMP accumulation...More data for this Ligand-Target Pair