null

SMILES Cc1c(CC(O)=O)c2cccnc2n1S(=O)(=O)c1ccc(F)c(c1)C#N

InChI Key InChIKey=XRMUPVMLIVXXAW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50296850   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataKi:  36nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Antagonist activity against CRTh2 receptor in human whole blood assessed as eosinophil shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Novartis Institutes of Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50296850(2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Antagonist activity against CRTh2 receptor in human eosinophils assessed as cell shape changeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1CCFPubMed