null

SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C

InChI Key InChIKey=XLDKAPYGJVCXCU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50300034   

TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300034(6,7-Dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NP4PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300034(6,7-Dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08H1PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300034(6,7-Dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 191nMAssay Description:Inhibition of human G9a catalytic domain (913 to 1193 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X350ZGPubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300034(6,7-Dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+6nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08H1PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50300034(6,7-Dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X350ZGPubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50300034(6,7-Dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of G9a by Alpha screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542NP4PubMed