null

SMILES Cc1c(Nc2c(cncc2-c2cc3cc(CN4CCNCC4)ccc3o2)C#N)ccc2[nH]ccc12

InChI Key InChIKey=DHUPFOOXPODTRC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302040   

TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302040(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetProtein kinase C theta type(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302040(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302040(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperazin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QR4Z2QPubMed