null

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Cl)cc2)n(n1)-c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=QMJQHTTXRJIVJD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303585   

TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Technical University of Dortmund

Curated by ChEMBL
LigandPNGBDBM50303585(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 856nMAssay Description:Inhibition of wild type DDR2 (unknown origin) preincubated for 30 mins before substrate addition by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z039P4PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303585(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Displacemnt of N,N'-(2,2'-(3,3'-disulfanediylbis(2,5-dioxopyrrolidine-3,1-diyl))bis(ethane-2,1-diyl))bis(2-(3-(3-tert-butyl-5-(3-naphthalen-1-ylureid...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0FKCPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of the Max Planck Society

Curated by ChEMBL
LigandPNGBDBM50303585(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of p38alpha active form expressed in Escherichia coli BL21(DE3) cells by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0FKCPubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Technical University of Dortmund

Curated by ChEMBL
LigandPNGBDBM50303585(1-(3-tert-butyl-1-(3-nitrophenyl)-1H-pyrazol-5-yl)...)copy SMILEScopy InChI
Affinity DataKd:  412nMAssay Description:Binding affinity to human acrylodan-labeled N-terminal His-tagged DDR2 (558 to 855 aa) by FLiK assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z039P4PubMed