null

SMILES Cc1n[nH]c2ncc(nc12)-c1cc(OC[C@@H](N)Cc2c[nH]c3ccccc23)cnc1-c1ccoc1C

InChI Key InChIKey=WVXVZSIOYIMDMF-SFHVURJKSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306154   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306154((2S)-1-(1H-indol-3-yl)-3-(5-(3-methyl-1H-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306154((2S)-1-(1H-indol-3-yl)-3-(5-(3-methyl-1H-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306154((2S)-1-(1H-indol-3-yl)-3-(5-(3-methyl-1H-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of GSK2beta phosphorylation in human BT474 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306154((2S)-1-(1H-indol-3-yl)-3-(5-(3-methyl-1H-pyrazolo[...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed