null

SMILES Cc1n[nH]c2ncc(nc12)-c1cc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c(nc1-c1ccoc1)C#N

InChI Key InChIKey=LAJHRQQVGFRLQL-SFHVURJKSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50306159   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306159((S)-3-(2-amino-3-(1H-indol-3-yl)propoxy)-6-(furan-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306159((S)-3-(2-amino-3-(1H-indol-3-yl)propoxy)-6-(furan-...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human AKT2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306159((S)-3-(2-amino-3-(1H-indol-3-yl)propoxy)-6-(furan-...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306159((S)-3-(2-amino-3-(1H-indol-3-yl)propoxy)-6-(furan-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK2beta phosphorylation in human BT474 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306159((S)-3-(2-amino-3-(1H-indol-3-yl)propoxy)-6-(furan-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human AKT3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8CXXPubMed