null
SMILES COc1ccc2n(C(=O)c3cccc(F)c3)c3CCN(CCCOc4cc(F)cc(c4)C4(CCOCC4)OC)Cc3c2c1
InChI Key InChIKey=JZAYARPHTUBBFJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50320708
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France
Curated by ChEMBL
Universit£ Lille-Nord de France
Curated by ChEMBL
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 production by HPLC methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£ Lille-Nord de France
Curated by ChEMBL
Universit£ Lille-Nord de France
Curated by ChEMBL
Affinity DataIC50: 3.57E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£ Lille-Nord de France
Curated by ChEMBL
Universit£ Lille-Nord de France
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£ Lille-Nord de France
Curated by ChEMBL
Universit£ Lille-Nord de France
Curated by ChEMBL
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of 5-hydroxyeicosatetraenoic acid production by HPLC methodMore data for this Ligand-Target Pair