null
SMILES CC(C)c1onc(c1COc1cnc(N(C)Cc2ccc(cc2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl
InChI Key InChIKey=BRVZXNBJNPVZTB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50323536
Affinity DataEC50: 242nMAssay Description:Agonist activity at human GST-fused FXR LBD assessed as cofactor peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at human full length FXR transfected in HEK293 cells coexpressing pTRexDest/pGL2promotor assessed as luciferase activity by direct r...More data for this Ligand-Target Pair
Affinity DataEC50: 107nMAssay Description:Agonist activity at human GST-fused FXR LBD expressed in HEK293 cells coexpressing GAL4-DNA bindig domain and pFRluc by mammalian one-hybrid assayMore data for this Ligand-Target Pair