null

SMILES Cc1ccccc1-n1c(Cn2nc(C#CCO)c3c(N)ncnc23)nc2cccc(C)c2c1=O

InChI Key InChIKey=GJBJSDBBRWPDBE-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50323730   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Medical Research Council-Laboratory of Molecular Biology

Curated by ChEMBL
LigandPNGBDBM50323730(2-((4-amino-3-(3-hydroxyprop-1-ynyl)-1H-pyrazolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of p110alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP82CKPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Medical Research Council-Laboratory of Molecular Biology

Curated by ChEMBL
LigandPNGBDBM50323730(2-((4-amino-3-(3-hydroxyprop-1-ynyl)-1H-pyrazolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of p110betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP82CKPubMed
LigandPNGBDBM50323730(2-((4-amino-3-(3-hydroxyprop-1-ynyl)-1H-pyrazolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
LigandPNGBDBM50323730(2-((4-amino-3-(3-hydroxyprop-1-ynyl)-1H-pyrazolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of p110deltaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Medical Research Council-Laboratory of Molecular Biology

Curated by ChEMBL
LigandPNGBDBM50323730(2-((4-amino-3-(3-hydroxyprop-1-ynyl)-1H-pyrazolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of p110gammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP82CKPubMed