null

SMILES CC(C)(CC(O)(Cc1cc2ccncc2[nH]1)C(F)(F)F)c1cccc(F)c1

InChI Key InChIKey=ANPFZNKOHNLVIS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50326953   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50326953(1,1,1-Trifluoro-4-(3-fluorophenyl)-4-methyl-2-(1H-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Binding affinity to glucocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by fluore...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571D0XPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50326953(1,1,1-Trifluoro-4-(3-fluorophenyl)-4-methyl-2-(1H-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Binding affinity to progesterone receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled RU-486 by fluorescence po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571D0XPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50326953(1,1,1-Trifluoro-4-(3-fluorophenyl)-4-methyl-2-(1H-...)copy SMILEScopy InChI
Affinity DataEC50: >2.00E+3nMAssay Description:Transactivation activity at glucocorticoid receptor in HFF assessed as induction of aromatase activity after 18 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571D0XPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50326953(1,1,1-Trifluoro-4-(3-fluorophenyl)-4-methyl-2-(1H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to mineralocorticoid receptor expressed in baculovirus-infected insect cells using tetramethylrhodamine labeled Dexamethasone by flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571D0XPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50326953(1,1,1-Trifluoro-4-(3-fluorophenyl)-4-methyl-2-(1H-...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Transrepression activity at glucocorticoid receptor in HFF assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571D0XPubMed