null

SMILES CC(=O)Nc1ccc(cc1)N=Nc1c(O)c2ccc(NC(=O)Nc3ccc4c(O)c(N=Nc5ccccc5)c(cc4c3)S(O)(=O)=O)cc2cc1S(O)(=O)=O

InChI Key InChIKey=ICIJDHUPWYQXGB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50328743   

TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataKi:  1.71E+3nMAssay Description:Binding affinity to His6x-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) using fluorescein-labeled H4(1-20) peptide substrate by spectrofluoro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-SAM by scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 7.42E+5nMAssay Description:Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using GAR R4 peptide and [14C]-AdoMet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of histidine tagged recombinant PRMT1 expressed in Escherichia coli BL21 (DE3) cells using Histone H4(1-20) substrate preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN96R4PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.77E+5nMAssay Description:Inhibition of His6x-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-11) and [14C]-SAM by scintillation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of HAT p300-mediated arginine methylation using H4(1-20) and [14C]-acetyl CoA by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetHistone-arginine methyltransferase CARM1(Mus musculus (mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of mouse GST-tagged CARM1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H3(1-31) and [14C]-SAM by scintilla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetProtein arginine N-methyltransferase 6(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibition of His6x-tagged PRMT6-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H3(1-31) peptide and [14C]-SAM by scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human GST-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-AdoMet by scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328743(3-((4-acetamidophenyl)diazenyl)-4-hydroxy-7-(3-(5-...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of His6x-tagged PRMT3-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using GAR R4 peptide and [14C]-SAM by scintil...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed