null

SMILES CO[C@@H]1COCC[C@@H]1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCN(CC1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=VBMPRCMEFUCQPO-SJHORNLWSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50337612   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte Corporation

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6C4CPubMed