null

SMILES COc1ccc(Cn2ncc(NC(=O)c3cc(NC(=O)Nc4ccc(Cl)c(c4)C(F)(F)F)ccc3C)c2N)cc1

InChI Key InChIKey=ZJDFSKSBQBPOSK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50338873   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.13nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.73nMAssay Description:inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.87nMAssay Description:inhibition of RAF1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 4.13nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 4.79nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 9.42nMAssay Description:inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 18.2nMAssay Description:inhibition of MEK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 21.5nMAssay Description:inhibition of FGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 51.6nMAssay Description:inhibition of IGF-1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Inhibition of C-Raf assessed as [33P]gamma-ATP incorporation into substrate after 40 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 167nMAssay Description:inhibition of PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:Inhibition of c-METMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 277nMAssay Description:inhibition of RONMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+3nMAssay Description:inhibition of JNK1a1 at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 3.02E+3nMAssay Description:inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of ERK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50338873(CHEMBL1684800 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.71nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CD3PubMed