null

SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(CC)C(=O)[C@@H](C)N(C)C1=O)C(C)C

InChI Key InChIKey=OLROWHGDTNFZBH-XEMWPYQTSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50339127   

TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataKi:  0.340nMAssay Description:Inhibition of human recombinant cyclophilin-associted cis-trans propyl isomerase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21836R5PubMed
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataKd:  1nMAssay Description:Binding affinity to human cyclophilin B by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed
TargetPeptidyl-prolyl cis-trans isomerase F, mitochondrial(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataKd:  1nMAssay Description:Binding affinity to human cyclophilin F by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in HEK293 cells using [3H]estradiol-17beta-glucuronide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of OATP1B3 (unknown origin) expressed in HEK293 cells using [3H]estradiol-17beta-glucuronide substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human MRP2 expressed in Sf9 cells inside out vesicles using CDCF substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed
TargetNonstructural protein 5A(Hepatitis C virus)TBA
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Inhibition of NS5A L31V mutant in HCV genotype 1b infected in HuH7.5Lcu-Neo cells assessed as reduction in viral replication by luciferase reporter g...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8WV9PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BCRP (unknown origin) expressed in T8 cells using Bodipy FL-prazosin substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of MDR1 (unknown origin) expressed in MDA T0.3 cells using rhodamine 123 substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of OATP1B1 (unknown origin) expressed in CHO cells using 8-fluorescein-cAMP substrate by fluorescent photometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataKd:  11nMAssay Description:Binding affinity to human cyclophilin A by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35VVCPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)TBA
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Inhibition of NS5B S282T mutant in HCV genotype 1b infected in HuH7.5Lcu-Neo cells assessed as reduction in viral replication by luciferase reporter ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8WV9PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataKd:  2.20nMAssay Description:Binding affinity to human cyclophilin A by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed
TargetBile salt export pump(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50339127((3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-d...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of BSEP (unknown origin) expressed in HEK293 cells using [3H]taurocholic acid substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5B1ZPubMed