null

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccccc4)cc3)c2cc1OC

InChI Key InChIKey=DHQJQTUHXYIGKP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50340929   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Univ Lille Nord de France, F-59000 Lille, France; UDSL, ICPAL, EA 4481, F-59006 Lille, France.

Curated by ChEMBL
LigandPNGBDBM50340929(1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WRVPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Univ Lille Nord de France, F-59000 Lille, France; UDSL, ICPAL, EA 4481, F-59006 Lille, France.

Curated by ChEMBL
LigandPNGBDBM50340929(1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human VEGFR-2-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C24WRVPubMed
LigandPNGBDBM50340929(1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant GST-CSF1R (residues L534 to C972) expressed in Sf9 insect cells using poly(Glu,Tyr) as substrate incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W3815DPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Univ Lille Nord de France, F-59000 Lille, France; UDSL, ICPAL, EA 4481, F-59006 Lille, France.

Curated by ChEMBL
LigandPNGBDBM50340929(1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR expressed in human A431 cells using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086695PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Univ Lille Nord de France, F-59000 Lille, France; UDSL, ICPAL, EA 4481, F-59006 Lille, France.

Curated by ChEMBL
LigandPNGBDBM50340929(1-(4-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-ph...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human VEGFR-2 using poly(Glu4/Tyr) and [gamma32P]ATP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086695PubMed