null

SMILES CNC(=O)Nc1ccc(Nc2nc3ccccc3n2-c2nc(C)nc(N)n2)cc1

InChI Key InChIKey=LYZVYVLSMGRTPB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50341035   

LigandPNGBDBM50341035(1-(4-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MBWPubMed
LigandPNGBDBM50341035(1-(4-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MBWPubMed
LigandPNGBDBM50341035(1-(4-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MBWPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50341035(1-(4-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of mTOR assessed as inhibition of phosphorylation of 4EBP1 by Lantha-Screen enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MBWPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50341035(1-(4-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of mTOR in human U-87 cells assessed as inhibition of phosphorylation of 4EBP1 at T37/46More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MBWPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50341035(1-(4-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of mTOR in human U-87 cells assessed as inhibition of phosphorylation of AKT at S473More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MBWPubMed
LigandPNGBDBM50341035(1-(4-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-b...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MBWPubMed