null

SMILES C[C@@H]1C[C@H](CN(C1)c1cc(nc(N)n1)-c1ccc2c(N)n[nH]c2c1)N(C)C(=O)CC(C)(C)C

InChI Key InChIKey=PCTRICLZSMFSET-GDBMZVCRSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50341250   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341250(CHEMBL1765751 | N-{(3R,5R)-1-[2-Amino-6-(3-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341250(CHEMBL1765751 | N-{(3R,5R)-1-[2-Amino-6-(3-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
TargetAurora kinase A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341250(CHEMBL1765751 | N-{(3R,5R)-1-[2-Amino-6-(3-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341250(CHEMBL1765751 | N-{(3R,5R)-1-[2-Amino-6-(3-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Inhibition of PDK1-mediated RSK phosphorylation at Ser221 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341250(CHEMBL1765751 | N-{(3R,5R)-1-[2-Amino-6-(3-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341250(CHEMBL1765751 | N-{(3R,5R)-1-[2-Amino-6-(3-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.631nMAssay Description:Inhibition of PDK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed
TargetAurora kinase B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50341250(CHEMBL1765751 | N-{(3R,5R)-1-[2-Amino-6-(3-amino-1...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ406QPubMed