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SMILES CC(C)Nc1ncc2cc(Oc3ccc(F)cc3F)c(=O)n(C)c2n1

InChI Key InChIKey=HAVJVJFXQRMACG-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341372   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto LLC

Curated by ChEMBL
LigandPNGBDBM50341372(6-(2,4-Difluorophenoxy)-2-isopropylamino-8-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant p38alpha assessed as incorporation of 33P from gamma-[33P]ATP into myelin basic protein after 30 mins by scintillatio...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Semmelweis University

Curated by ChEMBL
LigandPNGBDBM50341372(6-(2,4-Difluorophenoxy)-2-isopropylamino-8-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M6JPubMed