null
SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1
InChI Key InChIKey=RUPXKSLKGSSZCP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50343141
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Activation of FFA1 in mouse islets assessed as glucose-dependent insulin secretionMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 18.6nMAssay Description:Agonist activity at human FFA1 receptor expressed in human 1321N1 cells assessed as calcium mobilization by fluorescence spectrophotometryMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 6.31E+3nMAssay Description:Agonist activity at GPR120 assessed as stimulation of calcium mobilizationMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 12.9nMAssay Description:Agonist activity at FFAR1 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 30 mins by BRET assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 4(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 6.31E+3nMAssay Description:Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assayMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...More data for this Ligand-Target Pair
TargetFree fatty acid receptor 1(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 18.6nMAssay Description:Agonist activity at human GPR40 expressed in Flp-InTM T-RexTM HEK293 cells assessed as stimulation of calcium mobilizationMore data for this Ligand-Target Pair