null

SMILES Cn1c(CN2CC[C@@H](c3ccc(cc3)C(F)(F)F)C(C)(C)C2)nc2ncccc12

InChI Key InChIKey=KHCXQMDIHQPUSZ-KRWDZBQOSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343318   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343318((S)-2-((3,3-dimethyl-4-(4-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataKi: >2.80E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50343318((S)-2-((3,3-dimethyl-4-(4-(trifluoromethyl)phenyl)...)copy SMILEScopy InChI
Affinity DataEC50:  745nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222V3CPubMed