null

SMILES COc1cc(F)ccc1-c1cncc(CNC(=O)c2ccccn2)c1

InChI Key InChIKey=XEKZQVZQOZRWEJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50344260   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344260(CHEMBL1779013 | N-((5-(4-fluoro-2-methoxyphenyl)py...)copy SMILEScopy InChI
Affinity DataKi:  116nMAssay Description:Displacement of [3H]CP101606 from NR2B in rat brain minus cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887BKPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344260(CHEMBL1779013 | N-((5-(4-fluoro-2-methoxyphenyl)py...)copy SMILEScopy InChI
Affinity DataIC50: 673nMAssay Description:Antagonist activity at human NR2B expressed in HEK293 cells assessed as glutamate-induced changes in intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887BKPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344260(CHEMBL1779013 | N-((5-(4-fluoro-2-methoxyphenyl)py...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells electrophysiology studyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887BKPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344260(CHEMBL1779013 | N-((5-(4-fluoro-2-methoxyphenyl)py...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Iinhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887BKPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344260(CHEMBL1779013 | N-((5-(4-fluoro-2-methoxyphenyl)py...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Iinhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29887BKPubMed