null

SMILES Fc1ccc(NC(=O)NC23CC4CC(CC(C4)C2)C3)c(F)c1F

InChI Key InChIKey=PYDHHHKUANVSJV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50351247   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM50351247(CHEMBL1818385)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate after 10 mins by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69JZ1PubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM50351247(CHEMBL1818385)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KPPPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM50351247(CHEMBL1818385)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate preincubated for 5 mins followed by substrate addition and measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4TCDPubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM50351247(CHEMBL1818385)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant human liver soluble epoxide hydrolase expressed in baculovirus infected Sf21 cells using NEPC as substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2668HMVPubMed