null

SMILES Cn1cc(cn1)-c1ccc2c(c1)[nH]c1c(cnc(N[C@H](C3CC3)C(F)(F)F)c21)C(N)=O

InChI Key InChIKey=KFXMLXYIPRAORY-GOSISDBHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50355409   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50355409(CHEMBL1835142)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of JAK3 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43TGSPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50355409(CHEMBL1835142)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43TGSPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50355409(CHEMBL1835142)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in human HEL 92.1.7 irf1-bla cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43TGSPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50355409(CHEMBL1835142)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of JAK2 using biotin-EQEDEPEGDYFEWLE- NH2 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43TGSPubMed