null

SMILES CC(C)(C)CN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)n1

InChI Key InChIKey=MJQUKUIDCUNAAB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50374681   

TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374681(CHEMBL257834)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8ZWZPubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374681(CHEMBL257834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Erk2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8ZWZPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374681(CHEMBL257834)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of NIKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8ZWZPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374681(CHEMBL257834)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374681(CHEMBL257834)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of MK2-mediated HSP27 phosphorylation in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8ZWZPubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374681(CHEMBL257834)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of CLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8ZWZPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374681(CHEMBL257834)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8ZWZPubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374681(CHEMBL257834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MK2-mediated anisomycin-stimulated p38alpha phosphorylation in HeLa cells by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B8ZWZPubMed