null
SMILES CN(CC(=O)N(Cc1ccc(cc1)-c1ccc(cc1)-c1ccc(cc1)C(N)=O)c1ccc(C(O)=O)c(O)c1)S(=O)(=O)c1ccc(C)cc1
InChI Key InChIKey=KOVXOSJQVVRPFQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50382459
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto
Curated by ChEMBL
University of Toronto
Curated by ChEMBL
Affinity DataKi: 4.80E+3nMAssay Description:Displacement of 5-carboxyfluorescein-labeled GpYLVLDKW from the STAT5b-SH2 domain after 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto
Curated by ChEMBL
University of Toronto
Curated by ChEMBL
Affinity DataKi: 8.40E+3nMAssay Description:Displacement of fluorescein-labeled phosphotyrosine-peptide derived from the interleukin-6 receptor subunit gp130 from the STAT3 after 15 mins by flu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University of Toronto
Curated by ChEMBL
University of Toronto
Curated by ChEMBL
Affinity DataKi: 9.50E+3nMAssay Description:Displacement of radioligand from the STAT1 after 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto
Curated by ChEMBL
University of Toronto
Curated by ChEMBL
Affinity DataKi: 1.67E+4nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto
Curated by ChEMBL
University of Toronto
Curated by ChEMBL
Affinity DataKi: 1.67E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University of Southern California
Curated by ChEMBL
University of Southern California
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto
Curated by ChEMBL
University of Toronto
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair