null

SMILES CCCCNc1ncc2c(nn(C[C@H]3CC[C@H](N)CC3)c2n1)-c1ccc(F)cc1

InChI Key InChIKey=OGEBRHQLRGFBNV-RZDIXWSQSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50384576   

TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Inhibition of Mer using EFPIYDFLPAKKK-CONH2 as substrate by Michaelis-Menton equationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Centre Universitaire

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40WJPPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Mer expressed in Escherichia coli BL21 (DE3) cells using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Centre Universitaire

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QKCPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Centre Universitaire

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of Axl using KKKKEEIYFFF-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76DMCPubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of Tyro3 using EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by microfluid capillary electrophoresis assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76DMCPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MER (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of TYRO3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40WJPPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384576(CHEMBL2036808)copy SMILEScopy InChI
Affinity DataIC50: 141nMAssay Description:Inhibition of Mer autophosphorylation in human 697 cells pretreated for 1 hr before addition of phosphatase inhibitor measured by Western blot analys...More data for this Ligand-Target Pair