null

SMILES Cc1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1

InChI Key InChIKey=YYDUWLSETXNJJT-MTJSOVHGSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50384727   

TargetInsulin receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Tel-fused INSR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Tel-fused ROS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetTyrosine-protein kinase ZAP-70(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Tel-fused ZAP70 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetTyrosine-protein kinase receptor Tie-1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Tel-fused TIE1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of Tel-fused SRC in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetMacrophage-stimulating protein receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Tel-fused RON in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Tel-fused RET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of Tel-fused PDGFRbeta in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetTyrosine-protein kinase Lyn(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of Tel-fused LYN in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetHepatocyte growth factor receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Tel-fused MET in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetMast/stem cell growth factor receptor Kit(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Inhibition of Tel-fused KIT in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetMitogen-activated protein kinase 9(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Tel-fused JNK2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetInsulin-like growth factor 1 receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of Tel-fused IGF1R in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Tel-fused FMS in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Tel-fused FLT3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetVascular endothelial growth factor receptor 1(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of Tel-fused FLT1 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetTyrosine-protein kinase Fgr(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of Tel-fused FGR in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetFibroblast growth factor receptor 4(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Tel-fused FGFR4 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetFibroblast growth factor receptor 3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of Tel-fused FGFR3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetEphrin type-B receptor 2(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Tel-fused EPHB2 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetEphrin type-A receptor 3(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of Tel-fused EPHA3 in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of Tel-fused BMX in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetALK tyrosine kinase receptor(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Tel-fused ALK in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of TRKB by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of TRKA by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50384727(CHEMBL2037226)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of c-Kit in human Mo7e cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1MNMPubMed