null

SMILES Cc1nc(N)c2nnn(C[C@H]3CN(Cc4nccs4)CCO3)c2n1

InChI Key InChIKey=QGTJGTFOISKMAD-SNVBAGLBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50390334   

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL

LigandBDBM50390334(CHEMBL2070735)copy SMILEScopy InChI

Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67J0XPubMed

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL

LigandBDBM50390334(CHEMBL2070735)copy SMILEScopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67J0XPubMed

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL

LigandBDBM50390334(CHEMBL2070735)copy SMILEScopy InChI

Affinity DataIC50: 1.90nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLMCE
PC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67J0XPubMed