null

SMILES CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C

InChI Key InChIKey=YDOTUXAWKBPQJW-NSLWYYNWSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50390993   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50390993(CHEMBL1403281)copy SMILEScopy InChI
Affinity DataKi:  6.43E+3nMAssay Description:TP_TRANSPORTER: increase in Vinblastine intracellular accumulation in MDR1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95B7ZPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50390993(CHEMBL1403281)copy SMILEScopy InChI
Affinity DataKi:  1.22E+4nMAssay Description:TP_TRANSPORTER: increase in Calcein-AM intracellular accumulation in MDR1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W95B7ZPubMed
TargetATP-dependent translocase ABCB1(Mus musculus)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM50390993(CHEMBL1403281)copy SMILEScopy InChI
Affinity DataKi:  2.69E+4nMAssay Description:TP_TRANSPORTER: increase in Calcein-AM intracellular accumulation in mdr1b-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BH2PubMed
TargetATP-dependent translocase ABCB1(Mus musculus (Mouse))
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandPNGBDBM50390993(CHEMBL1403281)copy SMILEScopy InChI
Affinity DataKi:  4.35E+4nMAssay Description:TP_TRANSPORTER: increase in Calcein-AM intracellular accumulation in mdr1a-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8BH2PubMed
TargetCholecystokinin receptor type A(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50390993(CHEMBL1403281)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Concentration of compound required to inhibit binding of [125I]J-BH-CCK-8 radioligand to CCKA in mouse pancreatic membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P3242
LigandPNGBDBM50390993(CHEMBL1403281)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Concentration of compound required to inhibit binding of [125I]J-BH-CCK-8 radioligand to CCKB in mouse fore brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P3242