null

SMILES C[C@@H](Nc1ccccc1C(O)=O)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1

InChI Key InChIKey=IRTDIKMSKMREGO-OAHLLOKOSA-N

PDB links: 2 PDB IDs match this monomer.

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Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50395821   

LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ67PHPubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of human recombinant PI3Kgamma assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant PI3Kdelta assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP04F3PubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP04F3PubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as PIP3 production by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP04F3PubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of human recombinant His6-tagged PI3K p110alpha expressed in baculovirus infected cells using DiC8-PI(4,5)P2 as substrate after 20 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445NKMPubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of recombinant human PI3Kdelta assessed as reduction in PIP3 formation by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CRDPubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:ATP competitive inhibition of human recombinant PI3Kbeta assessed as PIP3 production by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1TPXPubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human PIK3CB by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD800FPubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human PI3Kalpha assessed as reduction in PIP3 formation by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CRDPubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human PI3Kbeta assessed as reduction in PIP3 formation by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CRDPubMed
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:Inhibition of recombinant human PI3Kgamma assessed as reduction in PIP3 formation by AlphaScreen assayMore data for this Ligand-Target Pair
LigandPNGBDBM50395821(CHEMBL2165191)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant His6-tagged PI3K p110beta expressed in baculovirus infected cells using DiC8-PI(4,5)P2 as substrate after 20 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445NKMPubMed