null
SMILES CC(C)c1nc(c([nH]1)-c1nc(C)cs1)-c1ccc2ncsc2c1
InChI Key InChIKey=DQPNJZAMZCNNEZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50402162
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of ALK5-mediated TNFalpha-induced Smad2/3 phosphorylation in human A549 cells preincubated for 2 hrs before addition of TNFalpha after 1 h...More data for this Ligand-Target Pair