null
SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1
InChI Key InChIKey=JFPVXVDWJQMJEE-IZRZKJBUSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 32 hits for monomerid = 50422689
Affinity DataKi: 1.04E+4nM IC50: 1.88E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
Affinity DataKi: 3.24E+4nM IC50: 5.64E+4nMpH: 6.5Assay Description:Enzymatic activity was determined spectrophotometrically by measuring the conjugation of CDNB with GSH. The 1 ml assay mixture contained 0.5 mM CDNB,...More data for this Ligand-Target Pair
Affinity DataKi: 3.27E+4nM IC50: 4.43E+4nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
TargetSolute carrier family 15 member 2(Homo sapiens (Human))
Universit£ degli Studi di Milano
Curated by ChEMBL
Universit£ degli Studi di Milano
Curated by ChEMBL
Affinity DataKi: 1.26E+7nMAssay Description:Binding affinity to human PepT2 in SKTP cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 2(Homo sapiens (Human))
Universit£ degli Studi di Milano
Curated by ChEMBL
Universit£ degli Studi di Milano
Curated by ChEMBL
Affinity DataKi: 1.26E+7nMAssay Description:Binding affinity to human PepT2 in SKTP cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 15 member 1(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Martin-Luther-University Halle-Wittenberg
Curated by ChEMBL
Affinity DataKi: 2.60E+7nMAssay Description:Binding affinity against membrane transport protein PEPT1 in human Caco-2 cellsMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 23.6nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP1AMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.36nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP1AMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 18.9nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP1AMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2XMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.82E+3nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2BMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 47.1nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP2XMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 4.71nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2XMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 402nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2BMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 89.5nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP2BMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 386nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP1AMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 9.43nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 24 PBP1AMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 14.1nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP1AMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 3.53E+4nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP2BMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP2XMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 0.0940nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2XMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 14.1nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2XMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 9.43nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP1AMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.18nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2BMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 14.1nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP1AMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2BMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 54.2nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2BMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.11E+3nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP2BMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 7.07nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2XMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 9.43nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2XMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 6.12E+3nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2BMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 4.71nMAssay Description:Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP1AMore data for this Ligand-Target Pair