null

SMILES FC(F)(F)c1ccccc1C(=O)N1CCN(CC1)c1ccc(nn1)C(=O)NCc1ccccc1

InChI Key InChIKey=CKIBNNYWZAXTRH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50424783   

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424783(CHEMBL2315104)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of SCD1 in human HepG2 cells using [14C]-stearate substrate assessed as decreased production of [14C]-oleic acid after 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424783(CHEMBL2315104)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Binding affinity to adenosine A1 receptor of rat brain membranes without NaCl by inhibition of [125-I]-labeled aminobenzyl adenosine bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N54F5PubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50424783(CHEMBL2315104)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N54F5PubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Xenon Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50424783(CHEMBL2315104)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of SCD1 in ICR mouse liver microsome using [9,10 3H]- stearoyl-Coenzyme A substrate assessed as decreased production of tritiated water af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4XDGPubMed