null
SMILES CCN(c1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1ccccc1
InChI Key InChIKey=IVNRPSKTRKQRGY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50426729
Affinity DataEC50: 10nMAssay Description:Binding affinity to LXRbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 190nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at GAL4-fused human PXR expressed in HEK293T cells assessed as activation of basal transcriptional activity after 20 hrs by dual-glo...More data for this Ligand-Target Pair
Affinity DataIC50: 245nMAssay Description:Displacement of [3H2]-25-hydroxycholesterol from N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial express...More data for this Ligand-Target Pair
Affinity DataEC50: 246nMAssay Description:Agonist activity at GAL4-fused human LXRbeta expressed in HEK293T cells assessed as activation of basal transcriptional activity after 20 hrs by dual...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity at GAL4-fused human LXRalpha expressed in HEK293T cells assessed as activation of basal transcriptional activity after 20 hrs by dua...More data for this Ligand-Target Pair
Affinity DataEC50: 1.08E+3nMAssay Description:Inverse agonist activity at pSG5GAL4-DBD/LBD fused human RORgamma receptor expressed in COS7 cells co-expressing 5 copies of GAL4 response element af...More data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Inverse agonist activity at GAL4-fused human RORa expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+3nMAssay Description:Inverse agonist activity at GAL4-fused human RORb expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 593nMAssay Description:Inverse agonist activity at GAL4-fused human RORc expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 320nMAssay Description:Binding affinity to LXRalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 930nMAssay Description:Inverse agonist activity at RORgamma in human CD4+ T cells assessed as inhibition of IL17A secretion after 72 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 9.00E+3nMAssay Description:Agonist activity at GAL4-fused human FXR expressed in HEK293T cells assessed as activation of basal transcriptional activity after 20 hrs by dual-glo...More data for this Ligand-Target Pair