BindingDB

null

SMILES Cc1c(F)c(ccc1C(=O)N1CCOc2ccc(cc2C1)-c1ccc(N)nc1)S(C)(=O)=O

InChI Key InChIKey=LNFBAYSBVQBKFR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 140 hits for monomerid = 50429867

Protein kinase C alpha type(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of PKCalpha (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

cGMP-dependent protein kinase 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of PKG1beta (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Mitogen-activated protein kinase 8(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of JNK1alpha1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Serine/threonine-protein kinase D2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of PKD2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Cyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of CDK5/P25 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Serine/threonine-protein kinase Chk1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

DNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 8.83E+3nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Serine/threonine-protein kinase BRSK1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of BRSK1 (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Protein kinase C eta type(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of PKCeta (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Protein kinase C beta type(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Tyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Aurora kinase A(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of Aurora kinase A (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of AKT3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

RAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of AKT2 (unknown origin)More data for this Ligand-Target Pair

PDB
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Mitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Tyrosine-protein kinase ABL2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of ARG (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Activated CDC42 kinase 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of ACK1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of RSK2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of IPFK2 (unknown origin)More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Fibroblast growth factor receptor 4(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Fibroblast growth factor receptor 3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Fibroblast growth factor receptor 2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Fibroblast growth factor receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 5.00E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 5.00E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 5.00E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Proto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Serine/threonine-protein kinase pim-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of PDGFRbeta (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Ribosomal protein S6 kinase beta-1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of p70S6K (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Hepatocyte growth factor receptor(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of KIT (unknown origin)More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Tyrosine-protein kinase JAK2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Heat shock protein HSP 90-beta(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of HSP90 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of FLT1 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Focal adhesion kinase 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of ERBB2 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Epidermal growth factor receptor(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

RAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.50E+3nMAssay Description:Inhibition of cRAF (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 3.00E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Details Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Death-associated protein kinase 3(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of ZIPK (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Details Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Tyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Details Article
BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Tyrosine-protein kinase Yes(Homo sapiens (Human))
Exelixis

Curated by ChEMBL

BDBM50429867(CHEMBL2333365)copy SMILEScopy InChI

IC50: 1.00E+4nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2ZC847XPubMed

Displayed 1 to 50 (of 140 total ) | Next | Last >>

Targets 137 ▿
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 2
- Protein kinase C beta type 2
- Mitogen-activated protein kinase 8 2
- Serine/threonine-protein kinase haspin 1
- Receptor tyrosine-protein kinase erbB-2 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1
- LIM domain kinase 1 1
- Hepatocyte growth factor receptor 1
- ALK tyrosine kinase receptor 1
- 5'-AMP-activated protein kinase subunit beta-1 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1
- Serine/threonine-protein kinase Nek7 1
- Glycogen synthase kinase-3 alpha 1
- Glycogen synthase kinase-3 beta 1
- Calcium/calmodulin-dependent protein kinase type 1 1
- Protein kinase C iota type 1
- Receptor-type tyrosine-protein kinase FLT3 1
- Serine/threonine-protein kinase Nek2 1
- Cell division cycle 7-related protein kinase 1
- Protein kinase C theta type 1
- MAP kinase-interacting serine/threonine-protein kinase 2 1
- Serine/threonine-protein kinase PAK 3 1
- Serine/threonine-protein kinase PAK 6 1
- Dual specificity mitogen-activated protein kinase kinase 1 1
- Tyrosine-protein kinase JAK2 1
- Serine/threonine-protein kinase 10 1
- Proto-oncogene tyrosine-protein kinase receptor Ret 1
- Dual specificity mitogen-activated protein kinase kinase 6 1
- Dual specificity mitogen-activated protein kinase kinase 7 1
- Dual specificity mitogen-activated protein kinase kinase 4 1
- Tyrosine-protein kinase ZAP-70 1
- Serine/threonine-protein kinase Sgk2 1
- Serine/threonine-protein kinase Sgk1 1
- Serine/threonine-protein kinase Sgk3 1
- Ephrin type-A receptor 2 1
- Tyrosine-protein kinase ITK/TSK 1
- DNA-dependent protein kinase catalytic subunit 1
- Tyrosine-protein kinase receptor UFO 1
- Protein kinase C eta type 1
- Insulin-like growth factor 1 receptor 1
- Tyrosine-protein kinase Blk 1
- Receptor-interacting serine/threonine-protein kinase 2 1
- Epidermal growth factor receptor 1
- Homeodomain-interacting protein kinase 2 1
- Serine/threonine-protein kinase NLK 1
- Ribosomal protein S6 kinase beta-1 1
- Phosphatidylinositol 3-kinase catalytic subunit type 3 1
- Casein kinase I isoform delta 1
- Nuclear receptor subfamily 2 group C member 2 1
- RAF proto-oncogene serine/threonine-protein kinase 1
- Tyrosine-protein kinase Lyn 1
- Focal adhesion kinase 1 1
- Heat shock protein HSP 90-beta 1
- Serine/threonine-protein kinase 33 1
- Ephrin type-B receptor 1 1
- Activated CDC42 kinase 1 1
- MAP kinase-activated protein kinase 2 1
- MAP kinase-activated protein kinase 3 1
- Platelet-derived growth factor receptor beta 1
- MAP kinase-activated protein kinase 5 1
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 1
- Muscle, skeletal receptor tyrosine-protein kinase 1
- Death-associated protein kinase 2 1
- Serine/threonine-protein kinase D2 1
- Serine/threonine-protein kinase D1 1
- PAS domain-containing serine/threonine-protein kinase 1
- Death-associated protein kinase 3 1
- Proto-oncogene tyrosine-protein kinase ROS 1
- Serine/threonine-protein kinase pim-1 1
- Serine/threonine-protein kinase TAO1 1
- Testis-specific serine/threonine-protein kinase 1 1
- Mitogen-activated protein kinase kinase kinase kinase 2 1
- Protein kinase C epsilon type 1
- Mast/stem cell growth factor receptor Kit 1
- Protein-tyrosine kinase 6 1
- Cyclin-dependent kinase 5 activator 1 1
- Mitogen-activated protein kinase kinase kinase 9 1
- Serine/threonine-protein kinase VRK2 1
- RAC-gamma serine/threonine-protein kinase 1
- Mitogen-activated protein kinase kinase kinase 5 1
- Interleukin-1 receptor-associated kinase 1 1
- Tyrosine-protein kinase ABL2 1
- Tyrosine-protein kinase ABL1 1
- RAC-alpha serine/threonine-protein kinase 1
- Rho-associated protein kinase 2 1
- cGMP-dependent protein kinase 1 1
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 1
- Rho-associated protein kinase 1 1
- Proto-oncogene tyrosine-protein kinase Src 1
- Tyrosine-protein kinase Fes/Fps 1
- Serine/threonine-protein kinase ULK2 1
- Mitogen-activated protein kinase 1 1
- Discoidin domain-containing receptor 2 1
- Serine/threonine-protein kinase 4 1
- Protein kinase C delta type 1
- SRSF protein kinase 3 1
- G protein-coupled receptor kinase 5 1
- Dual specificity protein kinase CLK2 1
- Protein-tyrosine kinase 2-beta 1
- Tyrosine-protein kinase Mer 1
- Serine/threonine-protein kinase N2 1
- Calcium/calmodulin-dependent protein kinase type IV 1
- Ribosomal protein S6 kinase alpha-2 1
- Ribosomal protein S6 kinase alpha-3 1
- Ribosomal protein S6 kinase alpha-1 1
- Serine/threonine-protein kinase TBK1 1
- Fibroblast growth factor receptor 4 1
- Vascular endothelial growth factor receptor 2 1
- Tyrosine-protein kinase HCK 1
- Aurora kinase A 1
- Fibroblast growth factor receptor 1 1
- Fibroblast growth factor receptor 2 1
- Fibroblast growth factor receptor 3 1
- Vascular endothelial growth factor receptor 1 1
- Serine/threonine-protein kinase PLK1 1
- Inhibitor of nuclear factor kappa-B kinase subunit beta 1
- Serine/threonine-protein kinase PLK3 1
- Inhibitor of nuclear factor kappa-B kinase subunit alpha 1
- Tyrosine-protein kinase receptor TYRO3 1
- RAC-beta serine/threonine-protein kinase 1
- Mitogen-activated protein kinase 10 1
- Serine/threonine-protein kinase BRSK1 1
- Protein kinase C gamma type 1
- Misshapen-like kinase 1 1
- Tyrosine-protein kinase CSK 1
- Ribosomal protein S6 kinase alpha-6 1
- Protein kinase C alpha type 1
- Ribosomal protein S6 kinase alpha-5 1
- Protein kinase C zeta type 1
- Serine/threonine-protein kinase Chk2 1
- Serine/threonine-protein kinase MARK1 1
- Serine/threonine-protein kinase Chk1 1
- Tyrosine-protein kinase Yes 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 2 1
- Serine/threonine-protein kinase WNK2 1
- Serine/threonine-protein kinase STK11 1
Publications 1 ▿
- J Med Chem 56: 2218-34 (2013) 140
Institutions 1 ▿
- [Exelixis] 140
Affinity: 3.0E+3 to 1.0E+4 nM▿
- IC50 140
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 1