null

SMILES Fc1ccc2[nH]cc(CCCNCc3ccccc3)c2c1

InChI Key InChIKey=RTLQUOXHRQJNMY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50432578   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Universit£ Libre de Bruxelles

Curated by ChEMBL
LigandPNGBDBM50432578(CHEMBL2347165)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZMZPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Universit£ Libre de Bruxelles

Curated by ChEMBL
LigandPNGBDBM50432578(CHEMBL2347165)copy SMILEScopy InChI
Affinity DataKi:  53nMAssay Description:Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1Z7TPubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£ Libre de Bruxelles

Curated by ChEMBL
LigandPNGBDBM50432578(CHEMBL2347165)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9ZMZPubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£ Libre de Bruxelles

Curated by ChEMBL
LigandPNGBDBM50432578(CHEMBL2347165)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1Z7TPubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£ Libre de Bruxelles

Curated by ChEMBL
LigandPNGBDBM50432578(CHEMBL2347165)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1Z7TPubMed