null

SMILES Oc1ccc(Cc2nnc3ccc(nn23)-c2ccc(F)cc2)cc1

InChI Key InChIKey=OEDWCZQOHLVVLK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50440886   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50440886(CHEMBL2431818)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Inhibition of c-Met (unknown origin) using poly Glu-Tyr as substrate preincubated for 10 mins followed by ATP addition by phosphoenolpyruvate/pyruvat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28919JGPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50440886(CHEMBL2431818)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Inhibition of N-terminal His-6-tagged human recombinant c-Met (974 to 1390) using Ac-ARDMYDKEYYSVHNK as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM59WRPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50440886(CHEMBL2431818)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of c-MET in human SNU-5 cells measured after 6 hrs by steady-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28919JGPubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50440886(CHEMBL2431818)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of c-Met autophosphorylation in human A549 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM59WRPubMed