null
SMILES Cc1csc(n1)[C@](C)(O)c1nnc(Nc2ccn(Cc3c(F)cccc3F)n2)s1
InChI Key InChIKey=UXRSVTXAGGLLHU-SFHVURJKSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50442997
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.
Curated by ChEMBL
AstraZeneca India Pvt. Ltd.
Curated by ChEMBL
Affinity DataKd: 12nMAssay Description:Binding affinity to Mycobacterium tuberculosis NADH-bound form of full length inhA (1 to 255) by SPR assayMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.
Curated by ChEMBL
AstraZeneca India Pvt. Ltd.
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of Mycobacterium tuberculosis full length inhA expressed in Escherichia coli BL21 preincubated for 15 mins by fluorescence based assay in ...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.
Curated by ChEMBL
AstraZeneca India Pvt. Ltd.
Curated by ChEMBL
Affinity DataKd: 9.30E+3nMAssay Description:Binding affinity to Mycobacterium tuberculosis NAD+-bound form of full length inhA (1 to 255) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
AstraZeneca India Pvt. Ltd.
Curated by ChEMBL
AstraZeneca India Pvt. Ltd.
Curated by ChEMBL
Affinity DataKd: 14nMAssay Description:Binding affinity to Mycobacterium tuberculosis NADH-bound form full length inhA (1 to 255) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair