null

SMILES Nc1nc(N)c2cc(NCc3ccc(CCNC(=O)c4ccc5OCOc5c4)cc3)ccc2n1

InChI Key InChIKey=RZEQSTAYIQIHAS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452177   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50452177(CHEMBL4207961)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of Plasmodium falciparum DHFR using DHF as substrate preincubated for 15 mins followed DHF addition measured after 15 mins by spectrophoto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QJXPubMed
TargetCysteine proteinase falcipain 2a(Plasmodium falciparum)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50452177(CHEMBL4207961)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Plasmodium falciparum FP2 using Z-Leu-Arg-AMC as substrate preincubated for 30 min followed by substrate addition measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50QJXPubMed