null
SMILES COc1cccc(F)c1-c1ccnc(Nc2ccc(cc2)S(=O)(=O)Nc2nnc(C)s2)n1
InChI Key InChIKey=LRXZVWVFJCSXSV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50454402
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human PLK1 kinase domain using 5-TAMRA-RGSFNDTLDFD-NH2 substrate and ATP incubated for 90 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal GST-HIS6 fusion protein tagged human full length CDK9 (M1 to F372 residues)/N-terminal GST-HIS6 fusion protein tagged human ...More data for this Ligand-Target Pair