null

SMILES CCC1CCc2nc3c(F)cc(cc3n12)-c1nc(Nc2ccc(CN3CCN(C)CC3)cn2)ncc1F

InChI Key InChIKey=YASYFVUJCWYQTN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50455074   

TargetCyclin-dependent kinase 6(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50455074(CHEMBL4217694 | US10696678, Example 67)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC4236PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
GAN & LEE PHARMACEUTICALS

US Patent
LigandPNGBDBM50455074(CHEMBL4217694 | US10696678, Example 67)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:In vitro inhibition of CDK (CDK1, CDK4, CDK6) activity by compounds of the present invention was tested by the following method.1. Preparation of kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q2439MUS Patent
TargetCyclin-dependent kinase 4(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50455074(CHEMBL4217694 | US10696678, Example 67)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK4 (unknown origin) after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC4236PubMed
TargetCyclin-dependent kinase 1/G1/S-specific cyclin-D3(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50455074(CHEMBL4217694 | US10696678, Example 67)copy SMILEScopy InChI
Affinity DataIC50: 5.05E+3nMAssay Description:Inhibition of recombinant human full length CDK1/Cyclin D3 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC4236PubMed