null
SMILES CC1(C)Cc2c(O1)c(cc1nc(Nc3c(F)cccc3Cl)[nH]c21)C(=O)Nc1cc(ccc1F)C(F)F
InChI Key InChIKey=PTRJVNVXIRTZMS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50460535
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 336nMAssay Description:Inhibition of mPGES1 in human whole blood assessed as reduction in LPS-induced PGE2 production measured after 20 to 24 hrsMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair