null

SMILES Cc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3ccc(F)c(c3)C(F)(F)F)c3OC(C)(C)Cc3c2[nH]1

InChI Key InChIKey=NMAXOPDWQJADOX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460543   

TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50460543(CHEMBL4226526)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta-induced PGE2 production preincubated for 30 mins followed by incubation wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300K5PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50460543(CHEMBL4226526)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300K5PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50460543(CHEMBL4226526)copy SMILEScopy InChI
Affinity DataIC50: 876nMAssay Description:Inhibition of mPGES1 in human whole blood assessed as reduction in LPS-induced PGE2 production measured after 20 to 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300K5PubMed