null

SMILES Cc1cn2c(cnc2c(Nc2cc(Cc3cnccn3)ns2)n1)-c1cn[nH]c1

InChI Key InChIKey=RWYBWOQOJKMXBT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460782   

TargetAurora kinase B(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50460782(CHEMBL4225385)copy SMILEScopy InChI
Affinity DataEC50:  208nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase A(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50460782(CHEMBL4225385)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Aurora A (unknown origin) using Tamra-PKAtide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50460782(CHEMBL4225385)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of Aurora B (unknown origin) using Tamra-PKAtide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed