null
SMILES Fc1ccc(N2CCN(CCCc3c[nH]c4ccc(F)cc34)CC2)c(c1)-c1ccccc1
InChI Key InChIKey=GPVZPQVIHIFYGO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50464867
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]LSD from recombinant human 5-HT7 receptor expressed in CHO cell membranes after 120 mins by TopCount scintillation counting metho...More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in HEK293 cell membranes after 60 mins by TopCount scintillation count...More data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:Displacement of [3H]prazosin from alpha1-adrenoceptor (unknown origin) in cerebral cortex membranes after 60 mins by TopCount scintillation counting ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human ERG expressed in CHO-K1 cells assessed as reduction in tail current amplitude at -80 mV holding potential after 2 mins by path cl...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]serotonin reuptake in rat brain synaptosomes SERT after 15 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL
Shanghai Institute of Pharmaceutical Industry
Curated by ChEMBL