null

SMILES CNc1nc(Nc2ccc(c(OC)c2)-n2cnc(C)n2)nc2N(CC(C)(C)c12)c1ccc(F)cc1

InChI Key InChIKey=KQAYMIJZYNJDEF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465355   

TargetAmyloid-beta precursor protein [672-713](Homo sapiens (Human))
HOFFMANN-LA ROCHE INC.

US Patent
LigandPNGBDBM50465355(CHEMBL4285214 | US10669276, Example 1)copy SMILEScopy InChI
Affinity DataEC50:  5nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ6928US Patent
TargetPresenilin-1(Homo sapiens (Human))
Temple University School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50465355(CHEMBL4285214 | US10669276, Example 1)copy SMILEScopy InChI
Affinity DataEC50:  5nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B055XPubMed