null
SMILES CCCS(=O)(=O)Nc1ccc(Cl)c(C(=O)Nc2cnc3[nH]nc(OC)c3c2)c1F
InChI Key InChIKey=VYNISSRXDZYNKV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50484231
Affinity DataIC50: 20nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of full-length B-Raf V600E mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of full length B-Raf V600E mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair