null
SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cccnc2)c1F
InChI Key InChIKey=FRMBYOWCMGOCQL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50484701
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of full-length B-raf V600E mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 6.73E+3nMAssay Description:Inhibition of B-raf V600E mutant-mediated Erk phosphorylation in human Malme3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair