null

SMILES COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N1CCN(C)CC1

InChI Key InChIKey=LDFAJFPHFKEJOI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50498655   

TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50498655(CHEMBL1895209)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of G9a (unknown origin) using [histone H3 1 to 25 residues] and SAM substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V127VKPubMed
LigandPNGBDBM50498655(CHEMBL1895209)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+5nMAssay Description:Inhibition of human NSD1-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43QPPubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50498655(CHEMBL1895209)copy SMILEScopy InChI
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D3059PubMed
TargetHistone-lysine N-methyltransferase NSD3(Homo sapiens (Human))TBA
LigandPNGBDBM50498655(CHEMBL1895209)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of human NSD3-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43QPPubMed
TargetHistone-lysine N-methyltransferase NSD2(Homo sapiens (Human))TBA
LigandPNGBDBM50498655(CHEMBL1895209)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human NSD2-SET using histone H3.1 as substrate incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43QPPubMed